Various oral sedatives have established efficacy and safety for managing fear and dental anxiety.
Anxiety and fear of going to the dentist persist despite the advancements in modern dentistry. Fortunately, oral sedatives in sedation dentistry have established efficacy and safety for managing dental anxiety. Oral sedatives can keep the patient awake while still having the desired calming effect.
Our adult daughter has cerebral palsy and requires being fully sedated when having anything done. The DAC was such a positive experience. Dr Hoffmann and his staff were kind and did great explaining things. As a mom, I had a lot of questions about how certain things would be done as usually she’s in her chair when getting examined at her local dentist and they had everything under control including transferring from her chair to the dentist chair and keeping her secured in the dentist chair as well as keeping her neck and legs comfortable. Many thanks to them!
Response from the owner:Thank you so much for your kind words. We’re grateful for your trust and happy to hear that you had such a positive experience with our team. Our goal is always to provide compassionate, attentive care in a safe and comfortable environment. We truly appreciate you taking the time to share your experience.
TWENTY YEARS! That is how long our special needs son has been seeing Dr Hoffman and his dedicated team! Our son suffers from an intellectual disability, is non-verbal, and is unable to cooperate for dental cleaning, x-rays, or other routine dental work. He requires general anesthesia. It is such a blessing to avoid a hospital setting just for dental work.
The team is always well staffed, friendly, personable and very professional. Every single year we have been supported by a deeply caring team who are dedicated to patients with a very wide range of disabilities and needs. They have shared useful dental advice and tools (3 sided toothbrushes, blocks to hold open their mouth for daily at-home care, etc.) which improved our son’s daily dental care. We always receive a call back the day after to check his recovery-even on weekends!
Highly recommended and so appreciative to have this team supporting our ever long road of raising a special needs son.
Response from the owner:Wow — thank you for sharing such a heartfelt review! We are so grateful for your trust and for allowing our team to be part of your family’s journey over the years. It means so much to us to know that our care and support have made a difference. We truly appreciate your kind words and recommendation!
We've been coming to Dr.Hoffman for twenty years. There's a reason we keep coming back! He's great. His staff is great. He's double boarded as an MD (Anesthesia) and DDS!!! Our son with special needs needs sedation for even a cleaning. You get what you pay for. He's expensive and... we know he's getting the best care!
Response from the owner:Thank you for trusting our team over the years and for your kind words about Dr. Hoffmann and our staff. We truly value your confidence in the care we provide!
Omg!! This place is Amazing! The people who work here are so very nice and understanding. I love this team
Response from the owner:Thank you so much for your kind words! We truly appreciate your support and are grateful to have such wonderful patients.
Searching for a new dental clinic is challenging for someone who has
dental anxiety, fear, and traumatic experiences in a dental chair. The staff and doctors at the Dental Anesthesia Center were immediately very welcoming. Dr. Thoms put together a very detailed plan to repair and replace the previous work that I had in the past that was now causing problems. Putting my faith in him was the best thing that I could have done for my situation. I am more than completely satisfied with all of the extensive dental work that I’ve had with Dr.Thoms. I had my fourth sleep dentistry experience yesterday and I’m very happy with my results. I highly recommend this practice and truly want to give them more than five stars! Thank you for giving me back my health and confidence.
Response from the owner:We know it isn’t always easy to find a dental office where you feel at ease, so your words mean the world to us. We’re so glad you feel comfortable with our team and truly appreciate your trust and recommendation!

There are many types of sedation used in sedation dentistry, ranging from mild sedation administered through a breathing mask to general anesthesia administered intravenously. There is a range of oral sedatives between these two options that can keep the patient awake while still having the desired calming effect.
If you are not sure what substances are used during sedation dentistry, here is a list of the most common oral drugs that a sedation dentist may prescribe for your dental treatment.
Midazolam (Versed)
Midazolam is the most commonly used drug in oral sedation dentistry, and it is generally considered very safe, inducing only a mild form of sedation. One precaution usually required when administering midazolam is to reschedule patients with respiratory infections for the day of the intervention, as this drug has a greater impact on the respiratory tract than on the circulatory system.
Diazepam (Valium)
One of the drugs almost everyone has heard about is diazepam (Valium). It is used in various medical interventions, including as an oral sedative for dental surgery. The time it takes for diazepam to remain in a 50% concentration in the patient’s system is longer than with other drugs, making it the preferred choice for extended, complex dental operations.
Triazolam (Halcion)
For patients who have a hard time going to the dentist because of their associated anxiety, triazolam is often the doctor’s choice. Primarily a drug that fights insomnia, it has an effect on the patient’s anxiety level and helps them go through the procedure without remembering it afterward, which allows them to be unaffected by their dental anxiety and come back next time.
Lorazepam (Ativan)
Another benzodiazepine with amnesic properties, like diazepam, lorazepam is very useful in patients with anxiety, allowing them to go through their dental treatment without the effects of their anxiety.
Hydroxyzine (Vistaril)
Hydroxyzine is an antihistamine that also acts on the patient’s anxiety levels. It is used short-term to treat anxiety or help a patient feel sleepy or relaxed before a dental procedure.
As you can see, there are many drug options if your St. Louis sedation dentist recommends oral sedation for your dental procedure. Which drug will be chosen depends on how long it takes for the medicine to get out of your system, your allergies and sensitivities, and what is needed from the sedation itself.
St. Louis Sedation Dentistry
For over 30 years, the Dental Anesthesia Center has combined sleep dentistry and cutting-edge technology to help patients overcome the fear and health issues that have prevented them from seeking dental care. We work hard to make you feel at ease by providing exceptional patient care in a relaxed, convenient atmosphere.
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The first two board-certified Dentist Anesthesiologists in the state of Missouri.