While nitrous oxide (also known as laughing gas) is generally safe, there are certain patients it is not recommended for.
Commonly known as laughing gas, nitrous oxide is a type of inhalation sedation that has been widely used in sedation dentistry since the 19th century when it was introduced to medicine. It is generally one of the safest substances that is used in sedation dentistry, as it’s effect doesn’t last long.
Our adult daughter has cerebral palsy and requires being fully sedated when having anything done. The DAC was such a positive experience. Dr Hoffmann and his staff were kind and did great explaining things. As a mom, I had a lot of questions about how certain things would be done as usually she’s in her chair when getting examined at her local dentist and they had everything under control including transferring from her chair to the dentist chair and keeping her secured in the dentist chair as well as keeping her neck and legs comfortable. Many thanks to them!
Response from the owner:Thank you so much for your kind words. We’re grateful for your trust and happy to hear that you had such a positive experience with our team. Our goal is always to provide compassionate, attentive care in a safe and comfortable environment. We truly appreciate you taking the time to share your experience.
TWENTY YEARS! That is how long our special needs son has been seeing Dr Hoffman and his dedicated team! Our son suffers from an intellectual disability, is non-verbal, and is unable to cooperate for dental cleaning, x-rays, or other routine dental work. He requires general anesthesia. It is such a blessing to avoid a hospital setting just for dental work.
The team is always well staffed, friendly, personable and very professional. Every single year we have been supported by a deeply caring team who are dedicated to patients with a very wide range of disabilities and needs. They have shared useful dental advice and tools (3 sided toothbrushes, blocks to hold open their mouth for daily at-home care, etc.) which improved our son’s daily dental care. We always receive a call back the day after to check his recovery-even on weekends!
Highly recommended and so appreciative to have this team supporting our ever long road of raising a special needs son.
Response from the owner:Wow — thank you for sharing such a heartfelt review! We are so grateful for your trust and for allowing our team to be part of your family’s journey over the years. It means so much to us to know that our care and support have made a difference. We truly appreciate your kind words and recommendation!
We've been coming to Dr.Hoffman for twenty years. There's a reason we keep coming back! He's great. His staff is great. He's double boarded as an MD (Anesthesia) and DDS!!! Our son with special needs needs sedation for even a cleaning. You get what you pay for. He's expensive and... we know he's getting the best care!
Response from the owner:Thank you for trusting our team over the years and for your kind words about Dr. Hoffmann and our staff. We truly value your confidence in the care we provide!
Omg!! This place is Amazing! The people who work here are so very nice and understanding. I love this team
Response from the owner:Thank you so much for your kind words! We truly appreciate your support and are grateful to have such wonderful patients.
Searching for a new dental clinic is challenging for someone who has
dental anxiety, fear, and traumatic experiences in a dental chair. The staff and doctors at the Dental Anesthesia Center were immediately very welcoming. Dr. Thoms put together a very detailed plan to repair and replace the previous work that I had in the past that was now causing problems. Putting my faith in him was the best thing that I could have done for my situation. I am more than completely satisfied with all of the extensive dental work that I’ve had with Dr.Thoms. I had my fourth sleep dentistry experience yesterday and I’m very happy with my results. I highly recommend this practice and truly want to give them more than five stars! Thank you for giving me back my health and confidence.
Response from the owner:We know it isn’t always easy to find a dental office where you feel at ease, so your words mean the world to us. We’re so glad you feel comfortable with our team and truly appreciate your trust and recommendation!

While it may seem perfectly harmless, laughing gas is still a sedative and should be taken only with a recommendation from your St. Louis sedation dentist, as it can have side effects when interacting with other medications or when administered to a person with an incompatible condition. That is why doctors choose the sedation option that is best for the patient instead of adapting the patient to the medication.
When Is Nitrous Oxide Recommended?
Laughing gas is often recommended when a patient has dentist anxiety or when he has to go through a long and tiring procedure. Sedation is an option also when the gag reflex is stronger than average or when the patient simply wants to make the treatment a bit easier to go through.
When it comes to patients that should not be put under stress, like patients with cardiac bypass or suffering from strong anxiety, administering nitrous oxide will generally make the dental procedure safer, as it takes away the associated stress.
Usually, young children that have to go through a dental procedure have trouble being still and patient for so long. Laughing gas can make the procedure possible.
Why It May Not Be Recommended
Although generally safe, there are times it should not be used. That’s why your St. Louis sedation dentist will check your medical history first before determining the best course of action.
Patients who have limited lung capacity or obstructive pulmonary disease should not be administered laughing gas. The safety of nitrous oxide is given by the fact that it acts quickly and wears out quickly as well. With these patients, however, the gas takes longer to act, as it is absorbed slower, and it leaves the body slowly as well. This greatly reduces the advantage of laughing gas has over other forms of sedation.
Patients who have a stuffy nose and are forced to breathe through their mouths may not be good candidates for nitrous oxide either. Laughing gas is administered through nasal airways and it won’t be as effective if the patient cannot breathe well through their nose.
Patients who cough are also to be administered other kinds of sedatives.
Pregnant women should not be administered nitrous oxide unless it is an emergency and the amount of sedatives is approved by an obstetrician. The toxicity of nitrous oxide to multiplying cells can be a threat to the fetus, especially in the first weeks of pregnancy.
Patients with intracranial disorders shouldn’t be administered laughing gas, as it can increase the pressure levels in the skull.
Additionally, if you take certain medications or you use drugs, you need to specify this to your doctor before being given laughing gas, as they might interact badly and manifest side effects.
Speak With The First Two Board Certified Dental Anesthesiologists in the State of Missouri
The bottom line is that it is extremely important to discuss all of your medical history with an experienced certified dental anesthesiologist before proceeding with treatment. To speak with the only certified dental anesthesiologists in the state of Missouri, call The Dental Anesthesia Center to day at (314) 862-7844.